BDBM50621475 CHEMBL5403404

SMILES CCCN1CCN(CC1)c1ccc2CCCC(N(C)C(=O)OCc3ccccc3)c2c1

InChI Key InChIKey=PBFDUYRSNDQIDN-UHFFFAOYSA-N

Data  40 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 50621475   

TargetSigma intracellular receptor 2(Rat)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma 2 receptor/TMEM97 in rat PC-12 cells assessed as inhibition constant in the presence of (+)-pentazoc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  20nMAssay Description:Binding affinity at human Histamine H1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-ditolylguanidine from human sigma 2 receptor/TMEM97 transfected in HEK293 cells assessed as inhibition constant in the presence ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  82nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells assessed as inhibition constant by competition binding as...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  100nMAssay Description:Binding affinity to human 5HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  135nMAssay Description:Binding affinity to human 5HT1D receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  156nMAssay Description:Binding affinity to human 5HT1A receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  200nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain assessed as inhibition constant by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  315nMAssay Description:Binding affinity to human 5HT2A receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  362nMAssay Description:Binding affinity to human 5HT1B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  438nMAssay Description:Binding affinity to human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  459nMAssay Description:Binding affinity to human 5HT7 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  690nMAssay Description:Binding affinity to human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  762nMAssay Description:Binding affinity to human 5HT2C receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  778nMAssay Description:Binding affinity to human 5HT6 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  1.03E+3nMAssay Description:Binding affinity to human alpha 2A adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity at human Histamine H3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  2.36E+3nMAssay Description:Binding affinity to human alpha 1A adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-1D adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to human alpha 1D adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  3.33E+3nMAssay Description:Binding affinity to human alpha 2B adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  3.96E+3nMAssay Description:Binding affinity to human dopamine D5 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  6.62E+3nMAssay Description:Binding affinity at human muscarinic M5 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  6.66E+3nMAssay Description:Binding affinity to human dopamine D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi:  8.33E+3nMAssay Description:Binding affinity at human PBR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBeta-3 adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human beta 3 adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1E receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human Norepinephrine transporter assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human SERT assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human dopamine D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human alpha 1B adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human DOR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human alpha 2C adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human beta 1 adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human beta 2 adrenergic receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human KOR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human muscarinic M1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human muscarinic M2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human muscarinic M3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human muscarinic M4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50621475(CHEMBL5403404)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human MOR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed