BDBM50621752 CHEMBL5396467
SMILES OC(=O)C1(CC1)c1cccc(c1)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1
InChI Key InChIKey=GFQRXOXNBQDNBC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50621752
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused ERbeta (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPeroxisome proliferator-activated receptor gamma(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PPARgamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs in presence of rosiglitazone by dual luciferase reporter as...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPeroxisome proliferator-activated receptor alpha(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pBIND-PPARalpha (unknown origin) transfected in HepG2 cells incubated for 18 hrs in presence of GW0742 by dual luciferase reporter assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFatty acid-binding protein, adipocyte(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from FABP4 (unknown origin) incubated for 3 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from FABP3 (unknown origin) incubated for 3 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FFA1 stably expressed in CHO cells assessed as intracellular calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused GR (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused MR (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused AR (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused PR (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetG-protein coupled bile acid receptor 1(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of TGR5 (unknown origin) transfected in human NCI-H716 cells assessed as increase in cAMP production incubated for 24 hrs by HTR-FRET assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused ERalpha (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of VP16-fused VDR-LBD (unknown origin) incubated for 18 hrs in presence of substrate by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused RARalpha (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Gal-DBD and NHRLBD fused RARgamma (unknown origin) transfected in African green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPeroxisome proliferator-activated receptor gamma(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs by renilla/firefly based dual-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPeroxisome proliferator-activated receptor alpha(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at pBIND-PPARalpha (unknown origin) transfected in HepG2 cells incubated for 18 hrs by renilla/firefly based dual-glo luciferase ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from FABP1 (unknown origin) incubated for 3 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 491nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 143nMAssay Description:Agonist activity at FXR-LBD (unknown origin) using fluorescein-coactivator peptide incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars