BDBM50621890 CHEMBL5415503
SMILES CCOc1cc(ccc1Nc1ncc2cc(-c3cccc(NC(=O)c4cccc(c4)C(F)(F)F)c3)c(=O)n(C[C@H]3CCCO3)c2n1)N1CCN(C)CC1
InChI Key InChIKey=RONKBVWJPIOCJX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 34 hits for monomerid = 50621890
Affinity DataKd: 44nMAssay Description:Binding affinity to PAK3 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 11nMAssay Description:Binding affinity to HCK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 20nMAssay Description:Binding affinity to JNK1 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 5.80nMAssay Description:Binding affinity to JNK2 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 23nMAssay Description:Binding affinity to JNK3 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 18nMAssay Description:Binding affinity to LCK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to MEK5 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 4.40nMAssay Description:Binding affinity to p38-alpha (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 9.40nMAssay Description:Binding affinity to p38-beta (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 1nMAssay Description:Binding affinity to GAK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 49nMAssay Description:Binding affinity to PYK2 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 11nMAssay Description:Binding affinity to SIK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 28nMAssay Description:Binding affinity to SRMS (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 67nMAssay Description:Binding affinity to TIE1 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 15nMAssay Description:Binding affinity to TNK1 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 39nMAssay Description:Binding affinity to TNNI3K (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 42nMAssay Description:Binding affinity to YES (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of KIT (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 219nMAssay Description:Inhibition of SRC (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 59nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by DiscoverX KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 101nMAssay Description:Inhibition of CSF1R (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of ABL (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of DDR1 (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 174nMAssay Description:Inhibition of DDR2 (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 71nMAssay Description:Inhibition of ZAK (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 28nMAssay Description:Inhibition of RET (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His6-tagged ACK1 (117 to 389 residues) (unknown origin) expressed in Sf9 cells using ATP as substrate incubated for 1 hrs by...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 23nMAssay Description:Binding affinity to EPHA3 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 15nMAssay Description:Binding affinity to EPHA8 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 10nMAssay Description:Binding affinity to EPHB6 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 16nMAssay Description:Binding affinity to ERBB4 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 34nMAssay Description:Binding affinity to FAK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 43nMAssay Description:Binding affinity to FGFR4 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 6.90nMAssay Description:Binding affinity to FRK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
