BDBM50622205 CHEMBL5397557::US20250353857, Compound TIA085

SMILES OCc1ccc(cc1)-c1cc2c(NCc3ccccc3)ncnc2[nH]1

InChI Key InChIKey=ACFWCPZFEIDRAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622205   

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622205BDBM50622205(CHEMBL5397557 | US20250353857, Compound TIA085)
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50622205BDBM50622205(CHEMBL5397557 | US20250353857, Compound TIA085)
Affinity DataIC50: 8.30nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50622205BDBM50622205(CHEMBL5397557 | US20250353857, Compound TIA085)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed