BDBM50622217 CHEMBL5432649::US20250353857, Compound TIA03-126

SMILES CN(Cc1ccccc1O)c1ncnc2[nH]c(cc12)-c1ccc(CO)cc1

InChI Key InChIKey=VSSCRMHSJRARCO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622217   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50622217BDBM50622217(CHEMBL5432649 | US20250353857, Compound TIA03-126)
Affinity DataIC50: 0.300nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50622217BDBM50622217(CHEMBL5432649 | US20250353857, Compound TIA03-126)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed