BDBM50622456 CHEMBL5409959::US12466809, Compound 24

SMILES Cc1cc(ccc1Nc1ncc(Br)c(Nc2cccc(F)c2C(N)=O)n1)S(=O)(=O)NCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

InChI Key InChIKey=ZOJWMCDSTRTTOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622456   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50622456BDBM50622456(CHEMBL5409959 | US12466809, Compound 24)
Affinity DataIC50: 6.5nMAssay Description:CDK2 and CDK5 IC50 data were attained through the use of Invitrogen™ commercial assays. The method for CDK2 (assay ID: 315, kinase|Z'-LYTE™|CDK2/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/2/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622456BDBM50622456(CHEMBL5409959 | US12466809, Compound 24)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 50622456BDBM50622456(CHEMBL5409959 | US12466809, Compound 24)
Affinity DataIC50: 6.80nMAssay Description:CDK2 and CDK5 IC50 data were attained through the use of Invitrogen™ commercial assays. The method for CDK2 (assay ID: 315, kinase|Z'-LYTE™|CDK2/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/2/2026
Entry Details
US Patent