BDBM50622716 CHEMBL5424443

SMILES CCOc1nn(c(NC(=O)N[C@H]2CN(CCOC)C[C@@H]2c2ccc(F)c(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=SQGLEZDWHPDRDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622716   

TargetHigh affinity nerve growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622716(CHEMBL5424443)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRKA (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622716(CHEMBL5424443)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of TRKB (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622716(CHEMBL5424443)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of TRKC (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed