BDBM50622718 CHEMBL5408454

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(cnc1-c1ccccc1)C(O)=O

InChI Key InChIKey=MLKKBTKDOPHWET-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622718   

TargetHigh affinity nerve growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622718(CHEMBL5408454)
Affinity DataIC50: 22nMAssay Description:Inhibition of TRKA (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622718(CHEMBL5408454)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of TRKB (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622718(CHEMBL5408454)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of TRKC (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed