BDBM50623376 CHEMBL5412018

SMILES Cn1cc(-c2nnc(N)nc2-c2c[nH]c3ccc(Br)cc23)c2cc(Br)cnc12

InChI Key InChIKey=FSQRVJNBMONDDZ-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50623376   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
University of Palermo

Curated by ChEMBL

LigandBDBM50623376(CHEMBL5412018)Copy SMILESCopy InChI

Affinity DataIC50: 210nMAssay Description:Inhibition of PDK1 (unknown origin) incubated for 30 mins followed by substrate addition measured after 60 mins in presence of ATP by ADP-Glo lumines...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL

LigandBDBM50623376(CHEMBL5412018)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant HSP90 incubated for 30 mins by fluorescence polarization based analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
University of Palermo

Curated by ChEMBL

LigandBDBM50623376(CHEMBL5412018)Copy SMILESCopy InChI

Affinity DataIC50: 30nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL