BDBM50624120 CHEMBL5422271

SMILES Cc1ccc(CNC(=O)c2cc(\C=C\C(O)=O)cc(c2)-c2ccc(cc2)-n2c3ccccc3c3ccccc23)cc1

InChI Key InChIKey=YZARZFGMYLKGPN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50624120   

TargetAldo-keto reductase family 1 member C3(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50624120(CHEMBL5422271)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50624120(CHEMBL5422271)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant AKR1C1 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50624120(CHEMBL5422271)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50624120(CHEMBL5422271)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant AKR1C4 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed