BDBM50624204 CHEMBL5483064

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(S)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@H]2C1F)O[C@H]3n1cnc2c1cn[nH]c2=O

InChI Key InChIKey=KETBVHVZGGXYJN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50624204   

TargetStimulator of interferon genes protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50624204(CHEMBL5483064)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human STING expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in interferon pr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50624204(CHEMBL5483064)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at human wild type STING overexpressed in STING knockout human THP1-Blue ISG cells expressing IRF inducible SEAP reporter construct ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50624204(CHEMBL5483064)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human STING in STING knockout human THP1-Blue ISG cells expressing IRF inducible SEAP reporter construct assessed as increase in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed