BDBM50624218 CHEMBL5425252

SMILES COc1ccccc1N1CCN(CCCNC(=O)NCc2ccccc2-c2ccccc2)CC1

InChI Key InChIKey=RGPTYLNPCNVHNC-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50624218   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopmaine D4.4 receptor expressed in HEK293T cells assessed as inhibition constant by competition bi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]prazosin from adrenergic alpha 1A receptor (unknown origin) expressed in HEK293T cells assessed as inhibition constant by competi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]WAY600135 from 5-HT1A receptor (unknown origin) expressed in HEK293T cells assessed as inhibition constant by competition binding...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopmaine D2S receptor expressed in CHO cell membrane assessed as inhibition constant by competition...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]RX821002 from adrenergic alpha 2A receptor (unknown origin) expressed in HEK293T cells assessed as inhibition constant by competi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor (unknown origin) expressed in HEK293T cells assessed as inhibition constant by competition bindin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopmaine D2L receptor expressed in CHO cell membrane assessed as inhibition constant by competition...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopmaine D3 receptor expressed in HEK293T cells assessed as inhibition constant by competition bind...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  480nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293T cells assessed as inhibition constant by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50624218(CHEMBL5425252)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK293T cells assessed as inhibition constant by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed