BDBM50625067 CHEMBL5404368

SMILES C=CC(=O)N1CC[C@H](C1)n1nc(Nc2ccc(Oc3ccccc3)cc2)c2c[nH]c3ncnc1c23

InChI Key InChIKey=CMFVTAHMZDUCJB-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50625067   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK (unknown origin) incubated for 140 mins in presence of ATP and [gamma-33p] ATP by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BMX (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 18nMAssay Description:Inhibition of TEC (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 771nMAssay Description:Inhibition of ITK (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 54nMAssay Description:Inhibition of TXK (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK3 (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 712nMAssay Description:Inhibition of EGFR (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 219nMAssay Description:Inhibition of ErbB2 (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 408nMAssay Description:Inhibition of ErbB4 (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein-tyrosine kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 500nMAssay Description:Inhibition of BRK (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Fgr(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 500nMAssay Description:Inhibition of FGR (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase FRK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 500nMAssay Description:Inhibition of FRK (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 500nMAssay Description:Inhibition of LCK (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of BTK phosphorylation at Y223 residue in goat F(ab') 2 anti-human IgM stimulated human Ramos cells by Western blotting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 11nMAssay Description:Inhibition of PLCgamma2 phosphorylation at Y1217 residue in goat F(ab') 2 anti-human IgM stimulated human Ramos cells by Western blotting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed