BDBM50625332 CHEMBL5407958

SMILES Cc1c(c(on1)C)COc2ccccc2C(=O)Nc3cccc(c3)Cl

InChI Key InChIKey=GBCRFZDGOAATHA-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50625332   

TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625332(CHEMBL5407958)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C1 (unknown origin) incubated for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625332(CHEMBL5407958)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C2 (unknown origin) incubated for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625332(CHEMBL5407958)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal His tagged AKR1C3 (unknown origin) expressed in Escherichia coli incubated for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625332(CHEMBL5407958)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C4 (unknown origin) incubated for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed