BDBM50626609 CHEMBL5221347

SMILES COc1ccc(Cl)c(c1)C(=O)NCC12CC3(F)CC(F)(CC(F)(C3)C1)C2

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50626609   

TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626609(CHEMBL5221347)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626609(CHEMBL5221347)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at mouse P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626609(CHEMBL5221347)
Affinity DataIC50: 25nMAssay Description:Inhibition of human P2X7 receptor in HEK cells by fluorescence based calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50626609(CHEMBL5221347)
Affinity DataIC50: 158nMAssay Description:Inhibition of mouse P2X7 receptor in HEK cells by fluorescence based calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed