BDBM50628024 CHEMBL5431801

SMILES [O-]C(=O)c1cc(Cl)c(Cl)cc1NC(=O)c1ccc(nn1)-n1ccc(c1)C#N

InChI Key InChIKey=PPYIDQMOABLOLL-UHFFFAOYSA-M

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50628024   

TargetStimulator of interferon genes protein(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50628024(CHEMBL5431801)
Affinity DataEC50:  2.99E+3nMAssay Description:Agonist activity at STING in PMA-differentiated wildtype human THP1-Blue ISG cells harboring IRF-inducible SEAP reporter construct incubated for 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50628024(CHEMBL5431801)
Affinity DataIC50: 4.58E+3nMAssay Description:Competitive inhibition of 5-FAM labelled diABZI binding to recombinant 6-his tagged mouse STING C-terminal domain (144 to 378 residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50628024(CHEMBL5431801)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in PMA-differentiated human THP1-Dual KO-STING cells incubated for 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed