BDBM50629084 CHEMBL5436466

SMILES N#Cc1ccc2[C@H](CCc2c1)Oc1ccc2[nH]nc(-c3cnco3)c2c1

InChI Key InChIKey=IHNLOAINBLZPTI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629084   

LigandPNGBDBM50629084(CHEMBL5436466)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate pre-incubated for 15 min and measured after 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629084(CHEMBL5436466)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human LRRK2 G2019S mutant phosphorylation at S1292 in human HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629084(CHEMBL5436466)
Affinity DataIC50: 27nMAssay Description:Inhibition of phosphorylated human LRRK2 G2019S mutant at S935 in human HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed