BDBM50629183 CHEMBL5428299

SMILES OC[C@@H](NC(=O)c1ccc2cnc(NC3CCOCC3)nc2n1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=QBUFHEYLXCCDOW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629183   

TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50629183(CHEMBL5428299)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to ERK2 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629183(CHEMBL5428299)
Affinity DataKi:  6.5nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed