BDBM50629383 CHEMBL5434549::US20250145619, Example 36

SMILES C[C@H]1CCN1c1nc2c(CCC2(F)F)c(n1)N1CC[C@H](CC(O)=O)C1

InChI Key InChIKey=PZTBTCUOQGBJRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629383   

TargetKetohexokinase(Human)
Tuojie Biotech (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal his tagged human recombinant KHK-C expressed in Escherichia coli incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetKetohexokinase(Human)
Tuojie Biotech (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 13.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent