BDBM50629737 CHEMBL5416266

SMILES O=C(NCCCN(Cc1nc2sc3CCCCc3c2c(=O)[nH]1)Cc1nc2sc3CCCCc3c2c(=O)[nH]1)c1cc2ccccc2c(=O)o1

InChI Key InChIKey=YLIXLTMOWMXIPA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50629737   

LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 4.18E+5nMAssay Description:Inhibition of human NSD1 SET domain using histone H3 as substrate assessed as reduction in H3K36 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human NSD2 SET domain using histone H3 as substrate assessed as reduction in H3K36 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human NSD3 SET domain using histone H3 as substrate assessed as reduction in H3K36 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of NSD2 (unknown origin) using H3K36 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 4.18E+5nMAssay Description:Inhibition of NSD1 (unknown origin) using H3K36 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629737(CHEMBL5416266)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of NSD3 (unknown origin) using H3K36 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed