BDBM50629809 CHEMBL5395142

SMILES CNc1nc(N\N=C\c2cccc3ccccc23)nc(Nc2cccc(c2)C(F)(F)F)n1

InChI Key InChIKey=QYLLDAJXAXGQDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629809   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629809(CHEMBL5395142)
Affinity DataIC50: 378nMAssay Description:Inhibition of human LRRK2 G2019S mutant using LRRKtide as substrate measured after 1 hrs by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629809(CHEMBL5395142)
Affinity DataIC50: 424nMAssay Description:Inhibition of human LRRK2 using LRRKtide as substrate measured after 1 hrs by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed