BDBM50630402 CHEMBL5400222

SMILES Nc1ccc2c(OCCOCCOc3ccc(F)c4nc(N)ccc34)cccc2n1

InChI Key InChIKey=AQEYGJVQPHADPK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630402   

TargetCytochrome b-245 heavy chain(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630402(CHEMBL5400222)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of NOX-2 dependent superoxide generation in PMA-differentiated human PLB-985 cells incubated for 1 hr by WST-1 based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630402(CHEMBL5400222)
Affinity DataKi:  9.53E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed