BDBM50630846 CHEMBL5402294::US20250320228, Example 46

SMILES COCCOc1ccc(-c2cc(C(N)=O)c3ncnc(N[C@H]4CCCNC4)c3n2)c(c1)C#N

InChI Key InChIKey=QNOGQHRAWNQBFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630846   

LigandChemical structure of BindingDB Monomer ID 50630846BDBM50630846(CHEMBL5402294 | US20250320228, Example 46)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50630846BDBM50630846(CHEMBL5402294 | US20250320228, Example 46)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HPK1 expressed in baculovirus infected Sf21 cells using MBP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed