BDBM50630851 CHEMBL5417582::US20250320228, Example 76

SMILES NC(=O)c1cc(nc2c(N[C@H]3CCCNC3)ncnc12)-c1ccc(F)cc1

InChI Key InChIKey=APCOQQQUKUHJIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630851   

LigandChemical structure of BindingDB Monomer ID 50630851BDBM50630851(CHEMBL5417582 | US20250320228, Example 76)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50630851BDBM50630851(CHEMBL5417582 | US20250320228, Example 76)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HPK1 expressed in baculovirus infected Sf21 cells using MBP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed