BDBM50631998 CHEMBL5399474

SMILES CCN1CCC(CN(C(=O)[C@@H]2CCN(Cc3ccccc3)C2)c2ccc(cc2)[As](O)O)CC1

InChI Key InChIKey=LXEHZSWUYHSECE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631998   

TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631998(CHEMBL5399474)
Affinity DataIC50: 122nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631998(CHEMBL5399474)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed