BDBM50632655 CHEMBL5410616

SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccc(NC(=O)Nc3ccccc3C)cc2)NC(=O)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC1=O)C(C)C)C(O)=O

InChI Key InChIKey=FXYDXLJEJBXFBD-UHFFFAOYSA-N

Data  6 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50632655   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50:  51nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as inhibition of fibronectin-induced cell adhesion pre-incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50:  35nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as inhibition of vascular cell adhesion molecule 1-induced cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50:  32nMAssay Description:Agonist activity at alpha4beta7 integrin receptor in human RPMI-8866 cells assessed as inhibition of mucosal vascular add-ressin cell adhesion molecu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50:  98nMAssay Description:Agonist activity at alpha1beta2 integrin receptor in human Jurkat E6.1 cells assessed as inhibition of ICAM-1-induced cell adhesion pre-incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as inhibition of fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 44nMAssay Description:Binding affinity to alpha4beta1 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibronectin coated well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 34nMAssay Description:Binding affinity to alpha4beta1 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in vascular cell adhesion ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 41nMAssay Description:Binding affinity to alpha4beta7 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in mucosal vascular add-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 83nMAssay Description:Binding affinity to alpha1beta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in ICAM-1 coated wells by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50632655(CHEMBL5410616)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alpha5beta1 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibronectin coated well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed