BDBM50632673 CHEMBL5430894

SMILES COc1cccc(Cn2nc(CNCc3cccc(OCc4ccccc4)c3)c3c2nc(-c2ccccc2Cl)c2cc(OC)c(OC)cc32)c1

InChI Key InChIKey=TUOBOJNLXPRSMI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632673   

TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50632673(CHEMBL5430894)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells assessed as inhibition constant incubated for 60 mins by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50632673(CHEMBL5430894)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells incubated for 60 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed