BDBM50633043 CHEMBL5406554

SMILES NC(=O)N1Cc2nc(-c3ccc(Cl)c(Cl)c3)n(c2C1)-c1ccnc(N[C@@H]2CCN(C2)C(=O)C2CC2)n1

InChI Key InChIKey=LGICVDGDWJJCIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50633043   

TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633043(CHEMBL5406554)
Affinity DataIC50: 3nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633043(CHEMBL5406554)
Affinity DataIC50: 230nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633043(CHEMBL5406554)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed