BDBM50633621 CHEMBL5424291

SMILES C[C@@H](Nc1cccc(F)c1C(O)=O)c1cc(C)cn2c1nc(N1CCC(F)(F)CC1)c(C#N)c2=O

InChI Key InChIKey=FQOSSODFWWGBLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633621   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633621(CHEMBL5424291)
Affinity DataIC50: 18nMAssay Description:Inhibition of AKT phosphorylation in human T47D cells harboring PI3Kalpha H1047R mutant incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed