BDBM50633764 CHEMBL5415819

SMILES Cn1ncc2ccc(NC(=O)c3nn(C4CC5(C4)CN(C5)C(=O)C=C)c4ccc(cc34)-c3cn[nH]c3)cc12

InChI Key InChIKey=ZYLZHHCYSDMOND-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633764   

TargetSon of sevenless homolog 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50633764(CHEMBL5415819)
Affinity DataEC50:  5.45E+3nMAssay Description:Agonist activity at SOS1 in human HeLa cells expressing wild type KRAS assessed as increase in p-ERK level incubated for 30 mins by Western blot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed