BDBM50634012 CHEMBL5436068

SMILES COc1cc(cc(OC)c1OC)-c1nccc2nc(Nc3cccc4n(C)ccc34)nn12

InChI Key InChIKey=CKEZRTNWKMKTJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634012   

TargetTyrosine-protein kinase JAK2(Human)
Wuyi University

Curated by ChEMBL
LigandPNGBDBM50634012(CHEMBL5436068)
Affinity DataIC50: 705nMAssay Description:Inhibition of JAK2 (unknown origin) using Poly-(Glu,Tyr 4:1) peptide as substrate in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Wuyi University

Curated by ChEMBL
LigandPNGBDBM50634012(CHEMBL5436068)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization measured for 30 mins in presence of GTP by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed