BDBM50637925 CHEMBL5559304

SMILES COc1cc(Nc2nccc(-c3cc(C(=O)N[C@@H](C)CN4CCC4)n(C)n3)n2)cc(OC)c1

InChI Key InChIKey=YLCFOHVAOBLAIK-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50637925   

TargetProtein kinase C beta type(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 239nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 980nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 802nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 798nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 3(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 738nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 697nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 567nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 450nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 257nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 182nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 79nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Mus musculus)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 7.83E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Mus musculus)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed