BDBM50637946 CHEMBL5518004

SMILES Cc1cccc(-c2nn3c(c2-c2ccc4ncnn4c2/C=C/C(N)=O)CCC3)n1

InChI Key InChIKey=FSQGWBXWGNWEAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50637946   

TargetTGF-beta receptor type-1(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637946BDBM50637946(CHEMBL5518004)
Affinity DataIC50: 40nMAssay Description:Inhibition of TGFbetaR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637946BDBM50637946(CHEMBL5518004)
Affinity DataIC50: 40nMAssay Description:Inhibition of TGFbetaR1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637946BDBM50637946(CHEMBL5518004)
Affinity DataIC50: 105nMAssay Description:Inhibition of human TGFbetaR1 expressed in HEK293 cells co-expressing SBE assessed as reduction in TGFbeta/activin A-induced SMAD phosphorylation pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed