BDBM50639390 CHEMBL5542501

SMILES CN(C)c1cccc(Nc2nccc(N3CCCn4nc(C#CC(C)(O)c5nccs5)cc43)n2)c1

InChI Key InChIKey=JTEXDTNZPAVSGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50639390   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639390(CHEMBL5542501)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639390(CHEMBL5542501)
Affinity DataIC50: 2.23E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639390(CHEMBL5542501)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed