BDBM50639412 CHEMBL5562073

SMILES COc1cc(Nc2nccc(N3CCCn4nc(C#C[C@@](C)(O)c5nccs5)cc43)n2)cc(OC)c1

InChI Key InChIKey=MMCBOQZHLAUWCX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50639412   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 1.19E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolycystin-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 4.03E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 2.88E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 5.41E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639412(CHEMBL5562073)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed