BDBM50640022 CHEMBL5568605

SMILES NC(=O)/C(=C\n2cnc(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)n2)c3cncnc3

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50640022   

TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640022BDBM50640022(CHEMBL5568605)
Affinity DataEC50:  7nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed