BDBM50641301 CHEMBL5574510

SMILES O=C(CBr)NCc1ccc(C(F)(F)F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50641301   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641301(CHEMBL5574510)
Affinity DataIC50: 183nMAssay Description:Covalent inhibition of NLRP3 in mouse BMDMs assessed as reduction in LPS/nigericin induced IL-1beta secretion pretreated with LPS for 3 hrs followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed