BDBM50645312 CHEMBL5574808

SMILES COc1cc(-c2cnc3nc2NCCCNS(=O)(=O)c2cc(ccc2OC)N3)ccc1F

InChI Key InChIKey=ULCIVHLQFMURQB-UHFFFAOYSA-N

Data  2 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50645312   

TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataKd:  95nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataKd:  6.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50:  1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 4(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50:  37nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50:  24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50:  3.40E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645312(CHEMBL5574808)
Affinity DataEC50:  4.20E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed