BDBM50647362 CHEMBL5598552

SMILES CCN1CCN(c2ccc(NC(=O)Nc3ccc(-c4cc(C(=O)NC)c5ncccc5n4)cc3)cc2C(F)(F)F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50647362   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 74nMAssay Description:Inhibition of FMS (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 484nMAssay Description:Inhibition of FLT3 (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 889nMAssay Description:Inhibition of TrkC (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 945nMAssay Description:Inhibition of FLT4 (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 958nMAssay Description:Inhibition of TrkA (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 992nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using myelin basic protein as substrate measured after 40 mins in presence of [gamma-33P]-ATP by scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50647362(CHEMBL5598552)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of NanoLuc-fused FMS (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed