BDBM50648544 CHEMBL5612298

SMILES CSc1nc2ccccc2n1C(=O)c1ccc(C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50648544   

TargetReplicase polyprotein 1ab(2019-nCoV)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50648544(CHEMBL5612298)
Affinity DataIC50: 390nMAssay Description:Inhibition of SARS-CoV-2 3CLpro using Dabcyl-KTSAVLQSGFRKM-Glu(Edans) as substrate preincubated for 1 hrs in presence of 2 mM GSH followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50648544(CHEMBL5612298)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of hCoV-229E 3CLpro using Dabcyl-KTSAVLQSGFRKM-Glu(Edans) as substrate preincubated 1 hr in presence of 2 mM GSH followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCalpain-1 catalytic subunit(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50648544(CHEMBL5612298)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human calpain 1 using (DABCYL)-TPLKSPPPSPR-(EDANS) as substrate incubated for 30 mins in presence of calcium ions and GSH and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed