BDBM50651041 CHEMBL5631367

SMILES Nc1ccccc1NC(=O)c1ccc(NC(=O)Cc2ccc(N3Cc4ccc(O)cc4OC3=O)cc2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50651041   

TargetMacrophage migration inhibitory factor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 180nMAssay Description:Inhibition of MIF (unknown origin) tautomerase activity incubated for 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 200nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 600nMAssay Description:Inhibition of C-terminl his-tagged human recombinant HDAC3 (1 to 428 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC2 (1 to 488 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed