BDBM50651836 CHEMBL5639271

SMILES Cc1cc(NC(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(Cl)cc2)ccc1Nc1cccc2c1OC(C)(C)C(=O)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50651836   

TargetHigh affinity nerve growth factor receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50651836(CHEMBL5639271)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50651836(CHEMBL5639271)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKB (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50651836(CHEMBL5639271)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKC (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50651836(CHEMBL5639271)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human recombinant TRKC G623R mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed