BDBM50652793 CHEMBL5653589

SMILES Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1943 hits for monomerid = 50652793   

TargetCUGBP Elav-like family member 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.0460nMAssay Description:Binding affinity to human CELF2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4B(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human EIF4B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C delta type(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.129nMAssay Description:Binding affinity to human PRKCD incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.132nMAssay Description:Binding affinity to human P4HA1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRNA cytosine C(5)-methyltransferase NSUN2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.187nMAssay Description:Binding affinity to human NSUN2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetUncharacterized protein FLJ45252(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human FLJ45252 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSRA stem-loop-interacting RNA-binding protein, mitochondrial(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.214nMAssay Description:Binding affinity to human SLIRP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.224nMAssay Description:Binding affinity to human CLK1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSmall ribosomal subunit protein uS4(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.236nMAssay Description:Binding affinity to human RPS9 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetER lumen protein-retaining receptor 1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.253nMAssay Description:Binding affinity to human KDELR1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRRP12-like protein(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.256nMAssay Description:Binding affinity to human RRP12 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.296nMAssay Description:Binding affinity to human CDK6 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTelomere length regulation protein TEL2 homolog(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.314nMAssay Description:Binding affinity to human TELO2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyosin light chain kinase, smooth muscle(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.317nMAssay Description:Binding affinity to human MYLK incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetATP-binding cassette sub-family E member 1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.362nMAssay Description:Binding affinity to human ABCE1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetQueuine tRNA-ribosyltransferase accessory subunit 2(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.411nMAssay Description:Binding affinity to human QTRTD1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcyl-protein thioesterase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.466nMAssay Description:Binding affinity to human LYPLA1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpithelial cell adhesion molecule(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.472nMAssay Description:Binding affinity to human EPCAM incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target26S proteasome non-ATPase regulatory subunit 5(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.486nMAssay Description:Binding affinity to human PSMD5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetElongation factor 1-gamma(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.491nMAssay Description:Binding affinity to human EEF1G incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNicotinate phosphoribosyltransferase(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.495nMAssay Description:Binding affinity to human NAPRT incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCollagen alpha-1(XIV) chain(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.577nMAssay Description:Binding affinity to human COL14A1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetUbiquilin-1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.598nMAssay Description:Binding affinity to human UBQLN1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSmall ribosomal subunit protein uS12(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.624nMAssay Description:Binding affinity to human RPS23 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.753nMAssay Description:Binding affinity to human NEK1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDnaJ homolog subfamily B member 12(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.810nMAssay Description:Binding affinity to human DNAJB12 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetImportin-11(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.820nMAssay Description:Binding affinity to human IPO11 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein SDA1 homolog(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.852nMAssay Description:Binding affinity to human SDAD1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.882nMAssay Description:Binding affinity to human CAMK2B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.888nMAssay Description:Binding affinity to human MAP2K5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetL-xylulose reductase(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.963nMAssay Description:Binding affinity to human DCXR incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAdenylosuccinate synthetase isozyme 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.991nMAssay Description:Binding affinity to human ADSS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSmall ribosomal subunit protein mS22(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1nMAssay Description:Binding affinity to human MRPS22 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTranslin(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1nMAssay Description:Binding affinity to human TSN incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetZinc finger protein 277(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1nMAssay Description:Binding affinity to human ZNF277 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNucleolysin TIAR(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human TIAL1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTELO2-interacting protein 1 homolog(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human TTI1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTubulin beta-4B chain(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human TUBB4B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStructural maintenance of chromosomes protein 1A(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human SMC1A incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C-binding protein 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human ZMYND8 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStearoyl-CoA desaturase 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human SCD5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 6 regulatory subunit 1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human PPP6R1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSyntaxin-binding protein 1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to human STXBP1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to human PRKCA incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGamma-tubulin complex component 3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human TUBGCP3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitochondrial import receptor subunit TOM70(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to human TOMM70A incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSperm-associated antigen 5(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to human SPAG5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEukaryotic translation initiation factor 3 subunit B(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to human EIF3B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  2nMAssay Description:Binding affinity to human NDUFS3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetZinc transporter 7(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  2nMAssay Description:Binding affinity to human SLC30A7 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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