BDBM50652935 CHEMBL5687006

SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc4c(c3)CCNC4)c(F)c2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652935   

TargetTyrosine-protein kinase ABL1(Human)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM50652935(CHEMBL5687006)
Affinity DataIC50: 9nMAssay Description:Inhibition of human N-terminal his tagged native ABL1 (229 to 499 residues) expressed in Sf9 cells using ABLtide as substrate preincubated for 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM50652935(CHEMBL5687006)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ABL1 T315I mutant (229 to 499 residues) using ABLtide as substrate preincubated for 2 hrs followed by ATP addition and measured e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed