BDBM50655688 CHEMBL6146262

SMILES CN(C(=O)[C@@H](NC(=O)C(F)(F)F)C1CC1)[C@@H](Cc1ccc(F)cc1)C(=O)N1C[C@]2(C[C@H]1C#N)C(=O)Nc1ccccc12

InChI Key InChIKey=NOCVUEORRDQZJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50655688   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655688BDBM50655688(CHEMBL6146262)
Affinity DataIC50: 21nMAssay Description:Inhibition of 6His-tagged SARS-CoV-2 3CLpro using Dabcyl-KNSTLQSGLRKE-Edans as substrate preincubated for 60 mins followed by substrate addition by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655688BDBM50655688(CHEMBL6146262)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of CTSL (unknown origin) incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCathepsin B(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655688BDBM50655688(CHEMBL6146262)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of CTSB (unknown origin) incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed