BDBM50656021 CHEMBL6133023

SMILES Cn1cc(-c2ccnc(Nc3cccc(N)c3)n2)c2ccccc21

InChI Key InChIKey=PIMQSUOWNYRXJT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50656021   

TargetTyrosine-protein kinase JAK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 27nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-biotin as substrate incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 173nMAssay Description:Inhibition of TYK2 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 337nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-biotin as substrate incubated for 120 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProcathepsin L(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656021BDBM50656021(CHEMBL6133023)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human Cat L using f Z-Phe-Arg-AMC as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed