BDBM50657269 CHEMBL6147405::US12643912, Example 13b

SMILES Cc1ccc2cc1[C@H]([N@@]3Cc4cc(ccc4OS3(=O)=O)OCCOCCn5c6ccc(c(c6nn5)C)[C@H]2CC(=O)O)C

InChI Key InChIKey=CAHCZMVBPKUGCY-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657269   

TargetKelch-like ECH-associated protein 1 [321-624](Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 50657269BDBM50657269(CHEMBL6147405 | US12643912, Example 13b)
Affinity DataKd:  4.15nMAssay Description:Binding assay to Kelch domain of KEAP1 was performed by Surface Plasmon Resonance (SPR) on a Biacore T200 (GE Healthcare) at 25° C. using CM5 chip. H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1 [321-624](Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 50657269BDBM50657269(CHEMBL6147405 | US12643912, Example 13b)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)