BDBM50658419 CHEMBL6161723

SMILES COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(N5CCC(N6CCN(C(=O)CCCNc7cccc8c7C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)CC5)cn5ncc(C#N)c45)cn2)C3)cn1

InChI Key InChIKey=VVEMQAOMKBCVAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50658419   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658419BDBM50658419(CHEMBL6161723)
Affinity DataIC50: 0.276nMAssay Description:Inhibition of RET (unknown origin) preincubated for 10 mins followed by substrate/ATP addition measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed