BDBM50659596 CHEMBL6163737

SMILES N#Cc1cccc(CN2CCc3[nH]c(=O)n(Cc4ccc(Cl)c(Cl)c4)c(=O)c3C2)c1

InChI Key InChIKey=DQSWREBDNVEGNC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50659596   

TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659596BDBM50659596(CHEMBL6163737)
Affinity DataEC50:  1.18E+3nMAssay Description:Activation of human ClpP using FITC-casein as substrate assessed as increase in proteolytic activity preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659596BDBM50659596(CHEMBL6163737)
Affinity DataKi:  5.11E+4nMAssay Description:Displacement of [3H]-N-methylspiperone from human D3 receptor extracted from HEK293 cell membrane assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659596BDBM50659596(CHEMBL6163737)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-N-methylspiperone from human D2L receptor extracted from HEK293 cell membrane assessed as inhibition constant incubated for 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed