BDBM50659754 CHEMBL6162602

SMILES C=CC(=O)Nc1ccc(Nc2nc(Nc3ccc(N4CCN(C)CC4)c(F)c3)ncc2Cl)cc1Cl

InChI Key InChIKey=GTVCPPIEOTTYPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50659754   

TargetFibroblast growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659754BDBM50659754(CHEMBL6162602)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FGFR1 V561M mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659754BDBM50659754(CHEMBL6162602)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of wild type FGFR1 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed